We used high resolution scanning electron microscopy to investigate Vero cells infected with SARS-CoV-2 at 2 and 48 hours post-infection.
The central conclusions of this work include:
Infected cells display polarization of their cytosol forming a restricted viroplasm-like zone dedicated to virus production and morphogenesis.
This is the first demonstration of SARS-CoV-2 attachment by scanning electron microscopy.
This is the first scanning electron microscopy images of the interior of SARS-CoV-2 infected cells and exploration of their vacuole contents.
Perspective-viewing of bordering vesicles in close association with vacuoles.
Observation of membrane ruffles and structures suggestive of exocytosis on the surface of infected cells.
The first demonstration of viral surfing in cell-to-cell communication on SARS-CoV-2 infection.
Source: https://www.biorxiv.org/content/10.1101/2020.06.10.144642v1
I found this thanks to Kevin W. McCairn Ph.D.
https://youtu.be/JisAV_i5yVQ
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