Melatonin And COVID-19: How Does This Medication Work And Can It Be Used As Adjunct COVID Therapy?


Whiteboard Doctor


Published on Nov 3, 2020

In this video we will discuss the medication Melatonin. This is a medication that is used throughout the word as an over the counter sleep aid and in the hospital for insomnia, assistance with sedation, and more. Earlier on in the pandemic there was discussion on wether this medication may be efficacious in COVID-19 as in vitro and animal studies it has been shown to have anti-inflammatory, anti-oxidant, and immunomodulation properties that have not been as well teased out in clinical studies. In this video, we will discuss these different properties and then dive into a trial that looked at Melatonin use in severe COVID-19. Interestingly, they found a decreased hazard ratio for a negative outcome in those that received Melatonin. What does this really mean? Check out the video for all the details!

Additional Therapies And COVID-19 (Monoclonal Antibodies, Pepcid, Melatonin, NAC, ACEI/ARBs)

Link to studies:

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There will be a running series of videos using the most up to date information on COVID-19, but this is an evolving field and new videos may come out that contradict that previous information. That is okay and is the nature of a fast paced and evolving clinical scenario. Stick with us as we work to unveil the intricacies of COVID-19, it's clinical significance, and the societal implications. ***This is strictly educational and not to be mistaken as clinical recommendations, please verify all information with accepted guidelines and practice patterns.***

THIS VIDEO DOES NOT PROVIDE MEDICAL ADVICE. The information, including but not limited to, text, graphics, images and other material contained on this website are for informational purposes only. No material on this site is intended to be a substitute for professional medical advice, diagnosis or treatment. Always seek the advice of your physician or other qualified health care provider with any questions you may have regarding a medical condition or treatment and before undertaking a new health care regimen, and never disregard professional medical advice or delay in seeking it because of something you have read, watched, or listened to on this video, or any other videos, reports, texts tweets or other sources.

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